/*--------------------css page------------------*/

.eos-calc-cta-sec .ocs-reduction-icon.lens{max-width:68px;}

.text-indent-4px {
    text-indent: -4px;
    padding-left: 4px;
}

.pl-1 {
    padding-left: 4px;
}

#study-designs-page ul.ocs-flex-items-cnt {
    padding-left: 15px;
}

#study-designs-page .acc-sum, #study-designs-page p.open-lable-txt {
    font-size: 16px;
    line-height: 20px;
    font-family: "myriad-pro";
    font-weight: 400;
    padding-right: 24px;
}

#study-designs-page p.open-lable-txt {
    padding-right: 12px !important;
}

#study-designs-page .acc-body-1, #study-designs-page .acc-body-2, #study-designs-page .acc-body-3, #study-designs-page p.predecessor-cnt  {
    font-size: 16px !important;
    line-height: 20px !important;
    font-family: "myriad-pro" !important;
    font-weight: 400 !important;
}

#study-designs-page .more-space {
    margin-bottom: 5px;
}

#study-designs-page .acc-foot {
    font-size: 14px;
    line-height: 16px;
    font-family: "myriad-pro";
    font-weight: 400;
}

#study-designs-page .acc-foot p {
    padding-bottom: 4px;
}

#study-designs-page .acc-foot-1 {
    padding-top: 4px;
}

#study-designs-page .pon-study-limit-list-item {
    font-size: 16px !important;
    line-height: 21px !important;
    font-family: "myriad-pro" !important;
    font-weight: 400 !important;
    padding-bottom: 5px;
}

#study-designs-page .inclus_crit, 
#study-designs-page .inclusion-criteria-sec p,
#study-designs-page .pon-study-limitations {
    font-size: 16px !important;
    line-height: 100% !important;
    font-family: "myriad-pro" !important;
    font-weight: 700 !important;
}

#study-designs-page p.melt-emi {
    font-size: 16px;
    line-height: 100%;
    font-family: "myriad-pro";
    font-weight: 700;
}

#study-designs-page ul#bora-inclusion-criteria li {
    font-size: 18px;
    line-height: 20px;
    font-family: "myriad-pro";
    font-weight: 400;
}

#study-designs-page ul.list-items-five-year .five-item {
    font-size: 16px;
    line-height: 20px;
    font-family: "myriad-pro";
    font-weight: 400;
    padding-right: 0;
}

#study-designs-page .span-acc-bold-title {
    font-size: 20px !important;
    line-height: 24px !important;
    color: #333F48;
    font-family: "myriad-pro", sans-serif; font-weight: 700; font-style: normal !important;
    /*font-weight: normal !important;*/
}

#study-designs-page div#real-world-evidence-accordion {
    margin-top: 20px;
    margin-bottom: 0;
}

#study-designs-page #acc-exa {
    margin-bottom: 0px;
}

#study-designs-page .acc-body-1, 
#study-designs-page .acc-body-2,
#study-designs-page .acc-body-3{
    padding-left: 0;
}

#study-designs-page #acc-exa:has(#acc-exa-item-9d0fb212f4) {
    margin-bottom: 30px;
}

@media screen and (min-width: 992px) {
    #study-designs-page .acc-image-ponente {
        padding: 0 50px;
    }
    
    #study-designs-page h3.aim-breathe-better {
		font-size: 40px;
		line-height: 44px;
		color: #FFFFFF;
		font-family: "myriad-pro-condensed", sans-serif; font-weight: 900; font-style: italic;
		max-width: 632px;
		margin-top: 14px;
		margin-bottom: 15px;
	}
    #study-designs-page .bottom-sec-eos {
        margin-bottom: -50px;
    }

    #study-designs-page .acc-image-ponente-xaloc-1 {
        padding: 0 75px;
    }
    
    #study-designs-page .special-flex {
        display: flex;
        gap: 95px;
    }
    
    #study-designs-page .acc-sum, #study-designs-page p.open-lable-txt {
        padding-right: 77px;
    }
    
    #study-designs-page #acc-exa-item-9d0fb212f4 .acc-sum {
        padding-right: 65px;
    }
    
    #study-designs-page #acc-exa {
        max-width: 1164px !important;
    }
    
    #study-designs-page .acc-body-1, #study-designs-page .acc-body-2, #study-designs-page .acc-body-3, #study-designs-page p.predecessor-cnt {
        padding-right: 0;
        /* padding-left: 0; */
    }

    #study-designs-page .fiv-year-cnt {
        padding: 0;
    }

    #study-designs-page .acc-body-1 {
        padding-right: 7px !important;
    }

    #study-designs-page .inclusion-criteria-sec {
        padding-top: 20px;
    }

    #study-designs-page p.study-melte-head {
        padding-top: 20px;
    }

    #study-designs-page .acc-body-1 {
        margin-top: 0;
    }
    
    #study-designs-page .acc-foot {
        padding: 0;
        max-width: 1107px !important;
    }

    #study-designs-page #text-b58c2e2464 > div.key-limitations.key-limitations1 > p.key-limit-content.key-limit-content3.pon-study-limitations {
        padding-top: 15px;
    }

    #study-designs-page .container-icon-moa.eos-calc-cta-sec {
        top: -86px;
    }

    #study-designs-page #text-a05018039c {
        padding-bottom: 0;
    }

    #study-designs-page p.acc-body-1.xaloc2 {
        font-size: 18px !important;
        line-height: 20px !important;
    }

    #study-designs-page p.acc-body-1.xaloc2 b {
        font-weight: 600 !important;
    }
    
    #study-designs-page .pon-study-limitations {
        padding-left: 0;
    }

    #study-designs-page .more-space {
        margin-bottom: 10px;
    }
    
    #study-designs-page #patient_zephyr_std .acc-foot {
        margin: 0;
        max-width: 1112px !important;
    }

    #study-designs-page ul.list-items-five-year {
        width: 51%;
    }

    #study-designs-page .five-year-list-items-section ul.list-items-five-year:first-child {
        width: 49%;
    }
    
    #study-designs-page .max-width-1120px {
        max-width: 1120px !important;
        margin: 0;
    }

    #study-designs-page .acc-foot p {
      padding-left: 0;
    }

    #study-designs-page p.acc-foot-1 {
        width: 101%;
    }

    #text-f3f18b07c0 {
        padding: 0;
    }

    #study-designs-page .pon-study-limitations.pon-study-limitations_ponente {
      margin-left: 0;
    }

    #study-designs-page .cmp-accordion__title {
      padding-left: 0 !important;
    }

    #study-designs-page #text-caf7d61333 > div > div > div > ul:nth-child(2) > li:nth-child(3) {
        padding-right: 40px;
    }

    #study-designs-page #common_patient .eos-eot-ics p {
        padding-left: 12px !important;
    }

    #study-designs-page .pon-study-limitations.pon-study-limitations_ponente .acc-body-1{
        padding-left: 0;
    }

    #study-designs-page #text-dfe51e5585 > div.key-limitations.list-elemen-one-cnt.list-elemen-one-cnt_std,
    #study-designs-page #text-b58c2e2464 > div.key-limitations.key-limitations1 {
        max-width: 100%;
    }

    #study-designs-page #text-5ceb30cacb > div:nth-child(5) {
        padding-bottom: 0;
    }

    #study-designs-page #text-dfe51e5585 > div.fiv-year-cnt > p:nth-child(2) {
        padding-right: 6px;
    }

    #study-designs-page #text-5ceb30cacb,
    #study-designs-page #text-c5f94ac9c4 {
        padding: 0 !important;
    }

    #study-designs-page #common_patient {
        margin-top: 10px;
    }

    #study-designs-page #accordion-7357ea270f-item-d03c896c37-button p.open-lable-txt {
        padding-right: 10% !important;
    }

    #study-designs-page #text-5ceb30cacb > div:nth-child(7) {
        margin-top: 0;
        margin-bottom: 15px;
    }

    #study-designs-page #text-a05018039c > div:nth-child(4),
    #study-designs-page #text-a05018039c > div:nth-child(5) {
        padding-bottom: 0;
    }

    #study-designs-page #text-a05018039c > div:nth-child(6),
    #study-designs-page #text-a05018039c > div:nth-child(5) {
        margin-top: 15px;
    }

    #study-designs-page #text-a05018039c > div:nth-child(6) {
        padding-bottom: 25px;
    }

    #study-designs-page .cta-wrapper {
        padding: 0 20px;
                gap: 10px;
    }

    #study-designs-page .cta-text-content {
        max-width: 279px;
    }

    #study-designs-page p.cta-icon {
        padding-right: 20px;
    }

    #study-designs-page .cta-wrapper.eosinophil-calc .chevron {
        top: 28px;
    }    
}

@media screen and (max-width: 991px) {

    #study-designs-page #accordion-7357ea270f-item-d03c896c37 .cmp-accordion__button {
        align-items: center;
    }

    #study-designs-page #acc-exa:has(#acc-exa-item-9d0fb212f4) {
        margin-bottom: 40px;
    }

    #study-designs-page .cmp-accordion__button,
    #study-designs-page .cmp-accordion__panel.cmp-accordion__panel--expanded {
        padding-left: 20px;
        padding-right: 20px;
    }

    #study-designs-page #acc-exa-item-2bbc85cb13-button .acc-sum,
    #study-designs-page #acc-exa-item-4cd1a12e63-button .acc-sum,
    #study-designs-page #acc-exa-item-9d0fb212f4-button .acc-sum {
        font-size: 14px;
        line-height: 16px;
    }

    #study-designs-page #acc-exa-item-4cd1a12e63-button .acc-sum {
        padding-right: 10px !important;
    }

    #study-designs-page #accordion-7357ea270f-item-d03c896c37-button > span.cmp-accordion__title > p.open-lable-txt {
        padding-right: 20px !important;
    }

    #study-designs-page #acc-exa-item-3ead2cc529-button > span.cmp-accordion__title > p > span.acc-sum {
        padding-right: 7px;
    }

    #study-designs-page #acc-exa-item-9d0fb212f4-button .acc-sum {
        padding-right: 11px;
    }

    #study-designs-page #text-d2716aedbd > p:nth-child(1) {
        padding-right: 5px;
    }

    #study-designs-page #text-dfe51e5585 > div.fiv-year-cnt {
        padding-right: 8px;
    }

    #study-designs-page .acc-body-1, #study-designs-page .acc-body-2, #study-designs-page .acc-body-3, #study-designs-page p.predecessor-cnt {
        font-size: 16px !important;
        line-height: 18px !important;
    }

    #study-designs-page #text-caa86b1ae6 > p.acc-body-1,
    #study-designs-page #text-9088cb4f80 > p,
    #study-designs-page #bora-inclusion-criteria > li:nth-child(2),
    #study-designs-page #text-5ceb30cacb,
    #study-designs-page #text-dfe51e5585 > div.key-limitations.list-elemen-one-cnt.list-elemen-one-cnt_std > ul > li:nth-child(3),
    #study-designs-page #text-a05018039c > div:nth-child(4) > p.acc-body-1 {
        padding-right: 6px;
    }

    #study-designs-page #text-5ceb30cacb > p.acc-body-1.pr-4_mobile,
    #study-designs-page #text-5ceb30cacb > div.acc-foot.max-width-1120px > p.acc-foot-1.pl-1,
    #study-designs-page #text-a05018039c > div.acc-foot > p.acc-foot-1.text-indent-4px,
    #study-designs-page #text-a05018039c > div.acc-foot > p.acc-foot-1.pl-1 {
        padding-right: 0;
    }

    #study-designs-page div#reference-section p {
        padding-right: 3px;
    }
    
    #text-5ceb30cacb > div.acc-foot.max-width-1120px > p.acc-foot-1.pl-1 {
        width: 102%;
    }

    #text-5ceb30cacb > div.acc-foot.max-width-1120px {
        padding-top: 15px;
    }

    #study-designs-page #text-8c236a2c08,
    #study-designs-page #text-d2561dd047,
    #study-designs-page #text-f3f18b07c0,
    #study-designs-page #text-b8a26b4be0,
    #study-designs-page #text-c5f94ac9c4 {
        padding: 0 !important;
    }

    #study-designs-page #patient_zephyr_std > div > p {
        padding-right: 0 !important;
    }

    #study-designs-page #text-bfce466350 > div > p.acc-foot-1 {
        padding-right: 2px;
    }

    #study-designs-page img.chevron {
        top: 26px !important;
    }

    #text-d6a1ee417d > div > div > a:nth-child(1) > div > div > p:nth-child(3) > img.chevron {
        top: 24px !important;
    }

    #study-designs-page div#real-world-evidence-accordion {
        margin-top: 0;
        margin-bottom: 0;
        border: 2px solid #EAEBEC;
        border-radius: 10px;
        margin-left: 16px;
        margin-right: 16px;
        margin-top: 7px;
    }

    #study-designs-page .cta-wrapper {
        margin-bottom: 10px;
    }

    #study-designs-page .cta-wrapper {
        padding: 10px 20px;
    }

    #study-designs-page .eos-calc-cta-sec .cta-test {
        margin-top: 25px;
    }

    #study-designs-page .eos-calc-cta-sec .cta-test.global-cta-btn2 {
        margin-bottom: 40px;
    }

    #study-designs-page #acc-exa {
        margin-top: 7px;
    }

    #study-designs-page h1.fas-eos-mob {
        margin-bottom: 20px;
                margin-top: 20px;
    }

    #study-designs-page #grey-background {
        background-color: #FAFAFA;
        padding: 30px 0 40px;
    }

    #study-designs-page #std_cta_top {
        margin-top: 42px;
    }

    #study-designs-page .bottom-sec-eos {
        margin-top: -75px;
    }

    #study-designs-page div#accordion-7357ea270f {
        margin-top: 7px;
        margin-bottom: 6px;
    }

    .mb-2_mobile {
        margin-bottom: 8px;
    }
    .pr-4_mobile {
        padding-right: 16px;
    }
    
    #study-designs-page .span-acc-bold-title {
        font-size: 18px !important;
        line-height: 100% !important;
        color: #333F48;
        font-family: "myriad-pro" !important;
        font-weight: 700 !important;
    }
    #study-designs-page #acc-exa-item-4cd1a12e63-button .acc-sum {
        padding-right: 0px;
    }
    #study-designs-page p.melt-emi.span-acc-bold-title {
        padding-right: 34px;
    }
    
    #study-designs-page .span-acc-bold-title_xaloc2 {
        padding-right: 30px !important;
    }

    body#study-designs-page .acc-image-1-title,
    body#study-designs-page .acc-image-2-title {
        padding-left: 51px !important;
    }
    
    #study-designs-page .acc-foot p {
        font-size: 14px !important;
        line-height: 16px !important;
        font-family: "myriad-pro" !important;
        font-weight: 400 !important;
        padding-right: 0;
    }

    #study-designs-page .acc-foot .acc-foot-1 {
        padding-right: 10px;
    }
    
    #study-designs-page .acc-foot.acc-foot_bora p {
        padding-right: 16px;
    }
    
    #study-designs-page ul#bora-inclusion-criteria li {
        font-size: 16px;
    }

    #study-designs-page #patient_zephyr_std .acc-foot p {
        padding-right: 12px;
    }
    
    
    #study-designs-page #accordion-7357ea270f-item-d03c896c37-button .cmp-accordion__button {
        display: flex;
        align-items: center;
    }

    #study-designs-page p.acc-image-1.mobile-only,
    #study-designs-page p.acc-image-2.mobile-only {
        max-width: 315px;
        margin: 0 auto;
    }
    #study-designs-page p.acc-image-2.mobile-only{
        margin-top:32px;
    }
}


#study-designs-page .cmp-text {
    font-family: "myriad-pro", sans-serif;
}