.publication-main {
    padding: 40px 0 0 0;
    
}

.publication-block {
    max-width: 1067px;
    margin: 0 auto;
    display: flex;
    justify-content: space-between;
}

.publication {
    width: 48.8%;
    padding: 26px 25px 23px 25px;
    border-radius: 5px;
    background: #FFFFFF;
    box-shadow: 0px 3px 6px #0000001A; border: 1px solid #E0E0E0;
}

.publication-view {
    display: flex;
    align-items: center;
    justify-content: space-between;
}

.publication-view-in {}

.publication-content { padding: 0 8px 0 0;}

.publication-content h5 {
    font-family: "myriad-pro", sans-serif; font-weight: 700; font-style: normal;
    font-size: 20px;
    line-height: 24px;
    color: #AE2573;
    margin: 0 0 5px 0;
}

.publication-content p {
    font-family: "myriad-pro", sans-serif; font-weight: 400; font-style: normal;
    font-size: 18px;
    line-height: 21px;
    color: #333F48;
}
.AsthmaSite#exacerbation-reductions .annual-exacerbation.unitalic h2 span.microliter-symbol{
    font-family: "myriad-pro", sans-serif; font-weight: 700; font-style: normal;
}
.publication-button {}

.publication-button a {
    display: block;
    border: 2px solid #AE2573;
    border-radius: 5px;
    padding: 8px 5px 5px 17px;
    color: #AE2573;
    font-family: "myriad-pro", sans-serif; font-weight: 700; font-style: normal;
    font-size: 16px;
    line-height: 18px;
    width: 164px;
    text-align: center;
}

.publication-button a:hover {
    color: #AE2573;
}

.publication-button a span {
    position: relative;
    display: inline-block;
    padding-right: 25px;
}

.publication-button a span::after {
    content: "";
    background: url(/content/dam/intelligentcontent/brands/fasenra-hcp/en/images/phase3/global/external-link-icon.svg);
    display: inline-block;
    width: 15px;
    height: 15px;
    background-repeat: no-repeat;
    right: 0;
    position: absolute;
    top: 1px;
     
}

.annual-exacerbation-head {
    padding: 30px 0 2px 0;
}

.annual-exacerbation p {
    font-size: 20px;
    line-height: 28px;
    font-family: "myriad-pro-condensed", sans-serif; font-weight: 400; font-style: italic;
    font-weight: normal;
    font-style: italic;
    color: #AE2573;
    padding: 0 0 4px 0;
}

#exacerbation-reductions .annual-exacerbation p {
    font-family: 'myriad-pro' !important;
    font-weight: 600 !important;
    font-size: 18px;
}

#exacerbation-reductions .bg-text-1-exa {
  font-size: 20px;
  line-height: 20px;
  margin-top: 0px;
  font-family: "myriad-pro-condensed", sans-serif; font-weight: 900; font-style: italic;
  text-transform: uppercase;
}

.annual-exacerbation h2 {
    font-size: 25px;
    line-height: 30px;
    font-family: "Myriad-pro";
    font-weight: 700;
    color: #333F48;
    margin: 0;
    padding-right: 10%;
}

#exacerbation-reductions .text-2-exa {
    font-size: 18px;
    line-height: 20px;
}

#exacerbation-reductions .cmp-text {
    font-family: 'Myriad-pro';
}

#exacerbation-reductions .acc-text3 {
    padding-left: 5px;
    padding-right: 0px;
}

#exacerbation-reductions .acc-text1 {
    padding-left: 0;
}

#exacerbation-reductions .acc-grp-text {
    padding-left: 5px;
}



.annual-head {
    background: transparent linear-gradient(90deg, #064C53 0%, #045F60 39%, #03746D 72%, #009D88 100%) 0% 0% no-repeat padding-box;
    border-radius: 10px 10px 0px 0px;
    padding: 12px 10px 11px 10px;
}

.annual-head h4 {
    font-family: "Myriad-pro";
    font-weight: 700;
    font-size: 18px;
    line-height: 22px;
    color: #FFFFFF;
    margin: 0;
    text-align: center;
}

.annual-content {
    background: #F7F7F7;
    padding: 30px 0 20px 0;
    border-radius: 0 0 10px 10px;
}

.annual-content-in {
    max-width: 1111px;
    margin: 0 auto;
    padding: 0 15px;
}

.placebo {}

.placebo figure {
    margin: 0; text-align: center;
}

.placebo-subgroup {

    padding: 20px 0 0 0;

    max-width: 755px;

    margin: 0 auto;
}

.placebo-subgroup p {
    font-family: "Myriad-pro";
    font-weight: 600;
    font-size: 16px;
    line-height: 18px;
    color: #333F48;
    margin: 0;
    text-align: center;
    padding: 0 0 18px 0;
}

.exacerbation-rate-main 
{
 padding: 55px 0 29px 0;
}
.exacerbation-rate 
{
   padding: 8px 0 0;
}
.exacerbation-rate p
{
    padding: 0 0 8px 0; 
    font-size: 14px;
    line-height: 18px;
}

.exacerbation-footnote 
{
    padding: 0;
}
.exacerbation-footnote p
{
    position: relative;
    padding: 0; 
    font-size: 14px;
    line-height: 18px;
}

.exacerbation-footnote p sup.astricp {  
    position: absolute;
    left: -5px;
}
/*NEW CSS*/
.unitalic {
    font-style: normal !important;
    font-family: "myriad-pro", sans-serif; font-weight: 400; font-style: normal !important;
}

.remove-background,#five-efficacy-page .remove-background {
    background: unset;
    color: #007260;
    border: 1px solid #DCDCDC;
    border-bottom: 4px solid #006F62;
    padding: 12px 0;
}

.img-background {
    background: none;
    border: 1px solid #DCDCDC;
    border-radius: 0 0 10px 10px !important;
    border-top: none;
    padding: 31.88px 96px 16.12px 84px;
    justify-content: space-between;
    align-items: center;
}

.img-background .img-exa {
    max-width: 486px;
    max-width: 49.66%;
    width: 100%;
}

.img-background .img-right-exa {
    max-width: 375px;
    max-width: 38.318%;
    width: 100%;
    position: relative;
}

.img-background .img-right-exa .text5-exa {
    font-family: "Myriad-pro";
    font-size: 20px;
    line-height: 120%;
    margin: 0;
    padding: 0;
}

#exacerbation-reductions .result-text {
    font-family: "Myriad-pro";
    font-size: 18px;
    line-height: 20px;
    font-weight: 600;
}   

.img-background .img-right-exa:before {
    content: '';
    position: absolute;
    display: block;
    left: -60px;
    height: 180px;
    width: 2px;
    top: 50%;
    transform: translateY(-50%);
    background: url(/content/dam/intelligentcontent/brands/fasenra-hcp/en/images/desktop/image-lins.svg) no-repeat;
    background-size: contain;
}

.remove-background h4 {
    color: #007260;
}

.annual-removebg {
    background: url();
    border: 1px solid #DCDCDC;
}

.img-background .img-exa img {
    object-fit: cover;
    width: 100%;
}

.pb-18 {
    padding-bottom: 18px;
}
#exacerbation-reductions .bg-text-2-exa {
    font-weight: 900;
    font-family: "myriad-pro-condensed", sans-serif; font-weight: 900; font-style: italic;
    max-width: 755px;
    padding-right: 9%;
    font-size: 40px;
    line-height: 44px;
    margin-top: 0px;
}

.mobile-only-br {
    display: none;
}

@media screen and (max-width: 391px) {
    .mobile-only-br {
        display: block;
    }
    #ocs-reduction-page .sec-container-two-ocs.content-center p.zonda .mobile-only-br{
    display:none;
}
}


@media screen and (min-width: 992px) {
    #exacerbation-reductions #accordion-exa #acc-exa 
    {
        margin-top: 50px;
    }

    .item-2-br {
        margin-left: -4px;
    }

    #exacerbation-reductions .text5-exa {
        text-indent: 0 !important;
        padding-right: 3%;
    }
.AsthmaSite#exacerbation-reductions .acc-text3{
   text-align:left;
    padding-left:0;
    padding-right:2px;
}
    #exacerbation-reductions .acc-text3,
    #exacerbation-reductions .acc-text2 {
        font-family: "Myriad-pro";
        font-weight: 400;
        font-size: 16px;
        line-height: 18px;
    }

    #exacerbation-reductions .acc-text2 {
        padding-right: 8%;
    }

    #exacerbation-reductions .acc-img1,
    #exacerbation-reductions .acc-img2 {
        max-width: 891px;
        margin: 16px auto 0;
    }
    
    #exacerbation-reductions .acc-img2 {
        margin-bottom: 32px;
    }
}

#exacerbation-reductions .acc-text6 {
    margin-top: 5px;
}
@media screen and (max-width: 1100px) {
    .publication { padding: 26px 15px 23px 15px; }

}
@media screen and (max-width: 991px) {

    #exacerbation-reductions .bg-text-2-exa {
        font-size: 32px;
        line-height: 36px;
    }

    body#exacerbation-reductions .bg-text-1-exa {
                margin-bottom: 5px;
    }

    #exacerbation-reductions .display-mob {
        padding-top: 11px;
    }

    #bottom-text-exa > div.exacerbation-rate-main > div > div > p:nth-child(3) {
        padding-right: 10px;
    }

    #exacerbation-reductions .span-bold-text_head {
        padding-right: 21%;
    }

    #exacerbation-reductions div#reference-section p {
        padding-right: 4px;
    }

    #exacerbation-reductions #text-d58796fde8 > div > div > div > h2 {
        font-size: 25px;
        line-height: 27px;
    }

    #exacerbation-reductions #accordion-exa {
        margin-top: 10px;
    }

    #exacerbation-reductions #bottom-text-exa > div.exacerbation-rate-main > div > div > p:nth-child(4) {
        padding-right: 2px;
    }

    #exacerbation-reductions .acc-img1-mob,
    #exacerbation-reductions .acc-img2-mob {
        max-width: 284px;
        margin: 16px auto 0;
    }

    #exacerbation-reductions .acc-text6,
    #exacerbation-reductions .acc-text7,
    #exacerbation-reductions .acc-text8 {
        font-size: 14px;
        line-height: 16px;
    }

    #exacerbation-reductions .acc-text7,
    #exacerbation-reductions .acc-text8 {
        padding-right: 10px;
    }

    #exacerbation-reductions .acc-text6 {
        padding-right: 20px;
    }

    #exacerbation-reductions .acc-img2-mob {
        margin-bottom: 15px;
    }

    #exacerbation-reductions #bottom-text-exa .container-icon-moa.eos-calc-cta-sec {
        margin-top: -57px !important;
    }

    #exacerbation-reductions .cta-wrapper {
        height: 88px;
    }
#exacerbation-reductions .global-cta-btn2 .cta-wrapper{
    padding-left: 26px;
}
#exacerbation-reductions .global-cta-btn2 .cta-wrapper .cta-icon{
   padding-right: 24px; 
}
    #exacerbation-reductions #acc-exa {
        margin-bottom: 63px !important;
    }

    #exacerbation-reductions .acc-text3 {
        padding-right: 11.5px;
    }

    #exacerbation-reductions .acc-text2 {
        padding-right: 9%;
        margin-bottom: 20px;
        margin-left: 5px;
    }

    #exacerbation-reductions .span-bold-text_head {
        margin-left: 5px;
        margin-top: 5px;
    }

    .annual-content {
        padding: 30px 0 15px 0;
    } 

    #exacerbation-reductions .text-2-exa {
        margin-top: 10px;
    }

    .annual-exacerbation h2 { 
        font-size: 20px;
        line-height: 22px;
        padding-right: 10%; 
        margin-bottom: 10px;
    }

    .annual-exacerbation-head { padding: 0 0 2px 0;}
    #exacerbation-reductions .bg-text-2-exa {
        padding-right: 10%;
        /*text-transform: uppercase;*/
        
    }
     #exacerbation-reductions .bg-text-2-exa span.text-uppercase {
            text-transform: uppercase;
        }
    .publication-block { display: block; max-width: 310px; margin: 0 auto;}
    .publication { padding: 24px 20px 21px 25px; width: 100%; margin: 0 0 20px 0;}
    .publication-content { padding:0 0 18px 0;}
    .publication-button a { margin:0 auto;} 
    .publication-view { display: block; margin: 0 0 8px 0;}
    .publication-content h5 { font-size: 18px; line-height: 22px;}
    .publication-content p { font-size: 16px; line-height:19px;}
    .pub-last { margin: 0;}

    .annual-exacerbation p { font-size: 16px; font-family: "myriad-pro", sans-serif; font-weight: 600; font-style: normal !important;} 

    

    .annual-head { padding: 15px 10px 14px 10px;} 
    .annual-head h4 { font-size: 18px; line-height: 19px;}
    .placebo-subgroup { padding: 20px 16px 0; }
    .placebo-subgroup p { font-size: 14px; line-height: 16px; padding: 0 0 10px 0;} 

    .placebo-subgroup p:last-child {
        font-size: 16px;
        line-height: 18px;
        margin-top: 15px;
    }

 .exacerbation-rate p
{
    padding: 0 0 5px 0; 
    font-size: 12px;
    line-height: 14px;
}

 
.exacerbation-footnote p
{
    padding: 0 0 5px 0; 
    font-size: 12px;
    line-height: 14px;
}
.exacerbation-rate-main 
{
 padding: 35px 0 40px 0;
}
.exacerbation-rate {
    padding: 5px 0 0;
}
#exacerbation-reductions .img-background {
    padding: 20px 0px 20px 15px;
    margin-bottom: 30px;
}

#exacerbation-reductions .img-exa,
#exacerbation-reductions .text5-exa,
#exacerbation-reductions .img-background .img-right-exa {
    max-width: 100%;
}

#exacerbation-reductions .img-background .img-right-exa:before {
    content: none;
}

#exacerbation-reductions .text5-exa {
    font-size: 18px;
    text-indent: 0;
}

}

/*Feedback 12-08-25 */

#exacerbation-reductions .lh-120 {
    line-height: 135%;
}

.text-indent-5px {
    text-indent: -5px;
}

@media screen and (max-width: 991px) {
    #exacerbation-reductions .img-exa {
        margin-bottom: 24px;
        border-bottom: 1.5px dashed #C5C5C5;
        padding-bottom: 24px;
    }
    
    #exacerbation-reductions .annual-exacerbation p {
        font-size: 16px;
    }
}