.remission-mandara-study-main {
    padding: 0;

}

.remission-mandara-study {
    padding: 33px 0 38px 0;
}

.remission-mandara-study-head {
    padding: 0 0 23px 0;
}

.remission-mandara-study-head p {
    /*font-weight: 500;*/
    font-size: 16px;
    font-family: "myriad-pro";
    font-weight: 400;
    line-height: 18px;
    color: #333F48;
    margin-bottom: 24px;
}
.remission-mandara-study-head h2 {
    margin: 0 0 2px 0;
    font-family: "myriad-pro-condensed", sans-serif; font-weight: 900; font-style: italic;
    font-size: 32px;
    line-height: 36px;
    color: #AE2573;
    text-transform: uppercase;
}
.remission-mandara-study-head h2 br { display: none; }
.remission-mandara-study-head figure {
    margin: 0;
}

.patients-remission-main {
    padding: 0;
    display: flex;
    justify-content: space-between;
    align-items: center;
}

.patients-remission {
    padding: 0;
    max-width: 596px;
    width: 100%;
}

.patients-remission h3 {
    margin: 0 0 17px 0;
    font-family: "myriad-pro", sans-serif; font-weight: 700; font-style: normal;
    font-size: 20px;
    line-height: 22px;
    color: #333F48;
}
#remission-data .patients-remission h3 span.pink-text{
font-family: "Myriad-pro";
font-weight: 700;
font-style: normal;
font-size: 20px;
line-height: 22px;
text-transform: uppercase;
color: #AE2573;
}
.achived-remission {
    border-radius: 12px 0px;
    border: 4px solid #881857;
    background: #FFFFFF;
    padding: 0;
}

.achived-remission-in {
    max-width: 596px;
    margin: 0 auto;
    text-align: center;
    padding: 34px 41px 18px;
}

.achived-remission-in h5 {
    margin: 2px 0 12px 0;
    font-family: "myriad-pro", sans-serif; font-weight: 700; font-style: normal;
    font-size: 20px;
    line-height: 100%;
    color: #333F48;
}

.achived-remission-in p {
    font-family: "myriad-pro", sans-serif; font-weight: 400; font-style: normal;
    font-size: 24px;
    line-height: 26px;
    color: #333F48;
}

.achived-remission-in p span {
    font-family: "myriad-pro", sans-serif; font-weight: 700; font-style: normal;
}


.achived-percentage>p {
    font-family: "myriad-pro", sans-serif;
    font-weight: 700;
    font-style: normal;
    font-size: 60px;
    line-height: 70px;
    background: linear-gradient(90deg, #840B55 0%, #AE2573 100%);
    background-clip: text;
    -webkit-background-clip: text;
    -webkit-text-fill-color: transparent;
    position: relative;
    text-align: center;
    margin-left: -15%;
    /* padding: 0 62px 0 0; */
}

.achived-percentage-2>p {
    font-family: "myriad-pro", sans-serif; font-weight: 400; font-style: normal;
    font-size: 48px;
    line-height: 58px;
    position: relative;
}

.achived-percentage>p>sub {
    font-family: "myriad-pro", sans-serif;
    font-weight: 700;
    font-style: normal;
    font-size: 35px;
    line-height: 35px;
    background: linear-gradient(90deg, #840B55 0%, #AE2573 100%);
    background-clip: text;
    -webkit-background-clip: text;
    -webkit-text-fill-color: transparent;
    position: absolute;
    bottom: 10px;
}

#remission-data .achived-percentage-2 {
    max-width: 209px;
    width: 100%;
}

#remission-data .achived-percentage {
    max-width: 221px;
    width: 100%;
}

#remission-data .flex-items {
    display: flex;
    justify-content: center;
    align-items: center;
    margin-top: 15px;
    gap: 28px;
}

#remission-data .vs-text {
    font-size: 24px;
    line-height: 26px;
    font-weight: 600;
    margin-bottom: 6px;
}

.achived-percentage-2>p>sub {
    font-family: "myriad-pro", sans-serif; font-weight: 700; font-style: normal;
    font-size: 35px;
    line-height: 35px;
    bottom: 10px;
}

.achived-percentage-2 .percentage {
    font-family: "myriad-pro", sans-serif; font-weight: 700; font-style: normal;
    font-size: 28px;
    line-height: 28px;
    bottom: 10px;
    position: absolute;
}

.achived-percentage>h3 {
    margin: -7px 0 16px 0;
    font-family: "myriad-pro", sans-serif;
    font-weight: 700;
    font-style: normal;
    font-size: 24px;
    line-height: 28px;
    color: #333F48;
    background: linear-gradient(90deg, #840B55 0%, #AE2573 100%);
    background-clip: text;
    -webkit-background-clip: text;
    -webkit-text-fill-color: transparent;
}

.achived-percentage-2>h3 {
    margin: -7px 0 16px 0;
    font-family: "myriad-pro", sans-serif; font-weight: 700; font-style: normal;
    font-size: 24px;
    line-height: 28px;
}

.achived-percentage-2 .normal-text {
    font-family: "Myriad-pro";
    font-size: 24px;
    line-height: 28px;
    margin: -10px 0 23px 0;
}

.patients-remission h6 {
    margin: 18px 0 0 0;
    /*font-family: "myriad-pro", sans-serif; font-weight: 700; font-style: normal;*/
   font-family: "Myriad-pro";
    font-weight: 700;
    font-size: 20px;
    line-height: 100%;
    color: #333F48;
    text-align: center;
    padding: 0px 1px;
}

.patients-remission-disease {
    padding: 0 60px 0 15px;
}

.remission-data-shapes {
    margin: 0;
    padding: 0;
}

.remission-data-shapes figure {
    margin: 0;
    text-align: center;
}

.remission-data-shapes figure {
    margin: 0 auto;

}

.patients-remission-disease h5 {
    margin: 24px 0 16px 0;
    padding: 0;
    font-family: "myriad-pro", sans-serif; font-weight: 700; font-style: normal;
    font-size: 22px;
    line-height: 24px;
    color: #AE2573;
    text-align: center;
}

.patients-remission-disease p {
    margin: 0;
    padding: 1px 0 10px 0;
    /*font-family: "myriad-pro", sans-serif; font-weight: 400; font-style: normal;*/
       font-family: "myriad-pro", sans-serif; font-weight: 400; font-style: normal;
    font-weight:400;
    font-size: 16px;
    line-height: 100%;
    color: #333F48;
    text-align: center;
}
.patients-remission-disease p > br{
    display:none;
}
.patients-remission-disease span {
    margin: 0px 0 9px 0;
    padding: 0;
    font-family: "myriad-pro", sans-serif; font-weight: 700; font-style: normal;
    font-size: 25px;
    line-height: 28px;
    color: #333F48;
    text-align: center;
    display: block;
}

.remission-data-shapes1 {
    margin-top: 8px;
}

.disease-activity-main {background-color: #FAFAFA;}

.reduce-ocs-patients-main {padding: 33px 0 40px 0;}

.reduce-ocs-patients-head {
    padding: 0 0 22px 0;
}

.reduce-ocs-patients-head h2 {
    margin: 0 0 1px 0;
    font-family: "myriad-pro-condensed", sans-serif; font-weight: 900; font-style: italic;
    font-size: 32px;
    line-height: 36px;
    color: #AE2573;
    text-transform: uppercase;
}

.reduce-ocs-patients-head figure {
    margin: 0;
}

.reduce-ocs-patients-head figure img {
    margin: 0;
}

.enpoint-data {
    padding: 10px 0 20px 0;
    max-width: 440px;
    margin: 0 auto;
}
.enpoint-data h3 {
    font-family: "myriad-pro", sans-serif; font-weight: 700; font-style: normal;
    font-size: 18px;
    line-height: 20px;
    color: #AE2573;
    text-align: center; margin: 0 0 8px 0;
}
.enpoint-data p {
    font-family: "myriad-pro", sans-serif; font-weight: 700; font-style: normal;
    font-size: 16px;
    line-height: 18px;
    color: #333F48;
    text-align: center;
}

.remission-data-tab {
    padding: 0;
}

.remission-data-nav {
    position: relative;
    padding: 0 10px;
    background-color: #FFFFFF;
    border: 2px solid #EDEDED;
    border-radius: 10px 10px 0px 0px;
    -webkit-box-shadow: -1px 7px 5px 0px rgba(237, 237, 237, 1);
    -moz-box-shadow: -1px 7px 5px 0px rgba(237, 237, 237, 1);
    box-shadow: -1px 7px 5px 0px rgba(237, 237, 237, 1);

}

.remission-data-tab .remission-data-nav ul {
    padding: 0;
    display: flex;
    align-items: center;
    justify-content: space-around;
    max-width: 655px;
    margin: 0 auto;
}

.remission-data-nav ul li {
    color: transparent;
    position: relative;
    width: 50%;
}

.remission-data-nav ul li::marker {
    color: transparent;
}
 
.remission-data-nav ul li a {
    font-family: "myriad-pro", sans-serif; font-weight: 700; font-style: normal;
    font-size: 20px;
    line-height: 22px;
    color: #333F48;
    text-align: center;
    padding: 27px 15px 24px 15px;
    display: block;
    position: relative;
    text-decoration: none;
}

.remission-data-nav ul li a span {
    display: block;
}


.remission-data-nav ul li a:hover,
.remission-data-nav ul li a:focus {
    color: #AE2573;
}

.remission-data-nav ul li.active a {
    color: #AE2573;
}


.remission-data-content-main {
    background-color: #FFFFFF;
    border-left: 1.5px solid #D7D7D7;
    border-right: 1.5px solid #D7D7D7;
    border-bottom: 1.5px solid #D7D7D7;
    border-radius: 0px 0px 12px 12px;
}


.remission-data-content {
    padding: 0;
}

.daily-dose-content {
    padding: 20px 30px 26px 30px;
}

.enpoint-mepolizumab {
    display: flex;
    max-width: 717px;
    margin: 0 auto;
    padding: 5px 0 0 0;
    justify-content: space-between;
    align-items: center;
}

.enpoint-graph {
    padding: 0 0 0 45px;
}

.enpoint-graph figure {
    margin: 0;
}

.enpoint-graph figure img {
    margin: 0;
}

.eliminated-content {
    padding: 0;
}

.daily-dose-shapes {
    padding: 0;
    margin: 0;
}

.daily-dose-shapes figure {
    padding: 0;
    margin: 0;
}

.daily-dose-shapes figure img {
    margin: 0 auto;
}

.enpoint-graph figure {
    padding: 0;
    margin: 0;
}

.enpoint-graph figure img {
    margin: 0 auto;
}

.eliminated-ocs {
    padding: 5px 0 17px 0;
}

.eliminated-ocs p {
    padding: 0;
    font-family: "myriad-pro", sans-serif; font-weight: 700; font-style: normal;
    font-size: 28px;
    line-height: 30px;
    color: #AE2573;
}

.eliminated-ocs p sup {
    font-family: "myriad-pro", sans-serif; font-weight: 700; font-style: normal;
    font-size: 28px;
    line-height: 28px;
    color: #AE2573;
    position: relative;
    top: 9px;
}

.eliminated-ocs h5 {
    font-family: "myriad-pro", sans-serif; font-weight: 600; font-style: normal;
    font-size: 16px;
    line-height: 18px;
    color: #AE2573;
    text-transform: uppercase;
    margin: 4px 0 4px 0;
}

.eliminated-ocs h4 {
    font-family: "myriad-pro", sans-serif; font-weight: 600; font-style: normal;
    font-size: 16px;
    line-height: 18px;
    color: #AE2573; 
    margin: 0 0 4px 0;
}

.eliminated-ocs h6 {
    font-family: "myriad-pro", sans-serif; font-weight: 700; font-style: normal;
    font-size: 16px;
    line-height: 19px;
    color: #AE2573;
    margin: 0;
}

.eliminated-content-in {
    text-align: center;
}

.eliminated-ocs-patients {
    padding: 0 0 16px 0;
}

.eliminated-ocs-patients p {
    font-family: "myriad-pro", sans-serif; font-weight: 700; font-style: normal;
    font-size: 28px;
    line-height: 27px;
    color: #333F48;
    padding: 0 0 0px 0;
}

.eliminated-ocs-patients h5 {
    font-family: "myriad-pro", sans-serif; font-weight: 600; font-style: normal;
    font-size: 14px;
    line-height: 15px;
    color: #333F48; 
    margin: 0 auto;
    max-width: 255px;
}

.enpoint-data1 {
    max-width: 543px;
}

.enpoint-mepolizumab1 {
    max-width: 760px;
}

.enpoint-graph1 {
    padding: 0 0 0 25px;
}

.investigator-main {
    padding: 0;
}

.investigator {
    padding: 22px 0 0 0;
    display: flex; align-items: center; flex-direction: row-reverse;
}

.discretion {
    padding: 0 34px 0 0;
    width: 44%;
}

.discretion h5 {
    font-family: "myriad-pro", sans-serif; font-weight: 700; font-style: normal;
    font-size: 18px;
    line-height: 22px;
    color: #333F48;
    padding: 0 0 9px 0;
    margin: 0;
}

.discretion p {
    font-family: "myriad-pro", sans-serif; font-weight: 400; font-style: normal;
    font-size: 16px;
    line-height: 19px;
    color: #333F48;
    padding: 0 0 2px 0;
    max-width: 479px;
}

.reducing {
    padding: 0;
    width: 56%;
    background: linear-gradient(90deg, rgba(174, 37, 115, 0.00) 0%, rgba(174, 37, 115, 0.10) 50%, rgba(174, 37, 115, 0.00) 100%);
}

.reducing-in {
    padding: 33px 15px 33px 15px;
    max-width: 380px;
    margin: 0 auto;
}

.reducing-in p {
    font-family: "myriad-pro", sans-serif; font-weight: 700; font-style: normal;
    font-size: 20px;
    line-height: 22px;
    color: #333F48;
    text-align: center;
}

.descriptive    { padding: 32px 0 0 0; }
.descriptive h5 {
    margin: 0 0 8px 0;
    font-family: "myriad-pro", sans-serif; font-weight: 600; font-style: normal;
    font-size: 16px;
    line-height: 19px;
    color: #253139; text-align: center;
}

.descriptive p {
    font-family: "myriad-pro", sans-serif; font-weight: 700; font-style: normal;
    font-size: 14px;
    line-height: 18px;
    color: #253139; text-align: center;
}
.abruptly
{
    padding: 0;
}
.abruptly p {
    font-family: "myriad-pro", sans-serif; font-weight: 700; font-style: normal;
    font-size: 14px;
    line-height: 16px;
    color: #253139; 
    text-align: center;
}

.disease-activity-head h2 {
    margin: 0 0 1px 0;
    font-family: "myriad-pro-condensed", sans-serif; font-weight: 900; font-style: italic;
    font-size: 32px;
    line-height: 36px;
    color: #AE2573;
    text-transform: uppercase;
}

.disease-activity-head figure {
    margin: 0;
}

.disease-activity-head figure img {
    margin: 0;
}

.disease-egpa{
    display: flex;
    flex-direction: column;
    height: 100%;
}
.disease-egpa-content {
    display: flex;
    flex-direction: column;
    justify-content: space-between;
    height: inherit;
   max-width: 86%;
}
.disease-egpa-content p {
    font-family: "myriad-pro", sans-serif; font-weight: 700; font-style: normal;
    font-size: 20px;
    line-height: 22px;
    color: #333F48;
}
.disease-egpa-content > p {margin-bottom: 8px;}

.disease-egpa-content h4 {
    font-family: "myriad-pro", sans-serif; font-weight: 700; font-style: normal;
    font-size: 20px;
    line-height: 22px;
    color: #AE2573;
    margin: 0;
    padding-top: 8px;
}
.disease-egpa-content > h4 {margin-bottom: 62px;}

.disease-activity {
    padding: 29px 0 38px 0;
    display: flex;
    justify-content: center;
}

.disease-activity-col {
    flex: 1;
    display: flex;
    flex-direction: column;
    gap: 30px;
}

p.result-descriptive {
    font-family: "myriad-pro", sans-serif; font-weight: 700; font-style: normal;
    font-size: 18px;
    line-height: 20px;
    color: #333F48;
    padding: 25px 0 0 0;
}

.achived-remission-activity .achived-remission-in {
    max-width: 580px;
}

.egpa-cta-footnote-remission-data {
    padding: 48px 0 35px 0;
}

.remission-data-icon img {
    margin-right: 10px;
}

.banner-remission-data { padding: 52px 0 51px 0;}
.achived-percentage-main { padding: 36px 0 23px 0; display: flex; justify-content: space-between;
    align-items: center;}
.achived-percentage-list { display: block; }
.achived-percentage-list > p { 
    /*font-family: "myriad-pro", sans-serif; font-weight: 700; font-style: normal; */
     font-family: "Myriad-pro"; 
    font-weight:700;
    font-size: 48px; 
    line-height: 48px; 
     color: #333F48;
    background:linear-gradient(90deg, #840B55 0%, #AE2573 100%);
    background-clip: text;
    -webkit-background-clip: text;
    -webkit-text-fill-color: transparent;  
}
.achived-percentage-list > p > span
{
 font-family: "Myriad-pro"; 
    font-size: 28px; 
    line-height: 28px; 
background:linear-gradient(90deg, #840B55 0%, #AE2573 100%);
background-clip: text;
-webkit-background-clip: text;
-webkit-text-fill-color: transparent;
}
.achived-percentage-list > h5 { 
    font-family: "myriad-pro", sans-serif; font-weight: 600; font-style: normal;    font-size: 24px; 
    line-height: 28px;  color: #333F48;
}
.achived-percentage-list-three p  
{
    color: #333F48;  background:linear-gradient(90deg, #333F48 0%, #333F48 100%);
    background-clip: text;
    -webkit-background-clip: text;
    -webkit-text-fill-color: transparent;   
}
.achived-percentage-list-three p span {
    color: #333F48; background: #333F48; background:linear-gradient(90deg, #333F48 0%, #333F48 100%);
    background-clip: text;
    -webkit-background-clip: text;
    -webkit-text-fill-color: transparent;   
}
.achived-percentage-list > h4
{
    font-family: "myriad-pro", sans-serif; font-weight: 700; font-style: normal; 
    font-size: 24px; 
    line-height: 28px; 
    background: linear-gradient(90deg, #840B55 0%, #AE2573 100%);
    background-clip: text;
    -webkit-background-clip: text;
    -webkit-text-fill-color: transparent; 
    margin: 0; 
    max-width: 221px;
}
.achived-percentage-list-one, .achived-percentage-list-three
{
    width: 43%;
}
.achived-percentage-list-three > h6
{
    font-family: "myriad-pro", sans-serif; font-weight: 400; font-style: normal;
    font-size: 20px;
    line-height: 24px;
    color: #333F48;
    margin: 0; 
    font-weight: 400;
}
.noninferiority-mandara > p { 
    font-family: "myriad-pro", sans-serif; font-weight: 700; font-style: normal; 
    font-size: 20px; 
    line-height: 22px;
    color: #333F48;
}

.remission-acc-body {
    display: flex;
    flex-direction: column;
    gap: 20px;
}
.remission-acc-body h2{
    color: #AE2573;
    font-family: "myriad-pro-condensed", sans-serif; font-weight: 900; font-style: italic;
    font-size: 32px;
    line-height: 36px;
    margin: 0;
}

    #remission-extra .remission-acc-body h2{
        /*font-family: 'myriad-pro';*/
        /*font-weight: 900;*/
    }
/*.remission-acc-body h2 sup{*/
/*        font-family: "myriad-pro-condensed", sans-serif; font-weight: 900; font-style: italic !important;*/
/*   }*/
.remission-acc-body h3{
    color: #333F48;
    font-family: "myriad-pro", sans-serif; font-weight: 700; font-style: normal; 
    font-size: 20px; 
    line-height: 22px;
    margin: 0;
}
.remission-acc-body p{
    color: #333F48;
    font-family: "myriad-pro";
    font-weight: 400;
    font-size: 18px; 
    line-height: 100%;
}
.remission-acc-body p span.semibold{
    font-family: "myriad-pro";
    font-weight: 600;
}

.remission-acc-body .acc-graphic .graphic-header{
    border-top-right-radius: 15px;
    border-top-left-radius: 15px;
    width: 100%;
    background: var(--Chart-header---Green-gradient, linear-gradient(90deg, #064C53 0%, #009D88 100%));
}
.remission-acc-body.remission-data .acc-graphic .graphic-header{padding: 14px 0;}
.remission-acc-body.ocs-reduction .acc-graphic .graphic-header{padding: 11px 0;}

.remission-acc-body .acc-graphic .graphic-header p{
    color: #fff;
    text-align: center;
    font-family: "myriad-pro";
    font-weight: 700;
    font-size: 20px;
    line-height: 100%;
}
.remission-acc-body .acc-graphic .graphic-body{
    border-bottom-left-radius: 15px;
    border-bottom-right-radius: 15px;
    border:2px solid #D7D7D7;
    border-top: 0;
    width: 100%;
    text-align: center;
    padding-top: 20px;
}
.remission-acc-body .acc-graphic{
    border-radius: 15px;
}
.remission-acc-body .acc-graphic img{
    max-width: 838px;
    width: 100%;
}
.remission-acc-body .acc-graphic .graphic-note{
    color: #333F48;
    font-family: "Myriad-pro";
    font-weight: 600;
    font-size: 18px;
    line-height: 22px;
    text-align: center;
    margin: 10px 0 20px;
}

.ocs-reduction-cards{
    display: flex;
    justify-content: center;
    gap: 20px;
}
.ocs-reduction-cards .data-card{flex: 1;}

.ocs-reduction-cards .data-card .card-heading{
    border-top-right-radius: 15px;
    border-top-left-radius: 15px;
    /*padding: 19px 0;*/
    padding: 15px 0;
    width: 100%;
    background: var(--Chart-header---Green-gradient, linear-gradient(90deg, #064C53 0%, #009D88 100%));
}
.ocs-reduction-cards .data-card .card-heading p{
    color: #fff;
    text-align: center;
    /*font-family: "myriad-pro", sans-serif; font-weight: 700; font-style: normal; */
   font-family: "Myriad-pro";
    font-weight: 700;
    font-size: 20px;
    line-height: 100%;
}
.ocs-reduction-cards .data-card .card-body{
    text-align: center;
    border-bottom-left-radius: 15px;
    border-bottom-right-radius: 15px;
    border:2px solid #D7D7D7;
    border-top: 0;
    padding: 9px 10px;
    min-height: 443px;
}
.ocs-reduction-cards .data-card .card-body p {
    font-family: "myriad-pro", sans-serif; font-weight: 700; font-style: normal; 
    color: #333F48;
    font-size: 16px;
    line-height: 100%;
    margin: 10px 0;
}
.ocs-reduction-cards .data-card .card-body .card-graph-1{max-width: 344px;}
.ocs-reduction-cards .data-card .card-body .card-graph-2{max-width: 314px;}


.reduce-ocs-patients .graphic-note {
    font-family: "Myriad-pro";
    font-weight: 600; 
    font-size: 18px;
    line-height: 22px;
    color: #253139;
    text-align: center;
    margin: 23px 0 12px;
}

.reduce-ocs-patients-main .reduce-ocs-patients .cards-note {
    font-family: "Myriad-pro";
    font-weight: 700; 
    font-size: 16px;
    line-height: 20px;
    color: #253139;
}

.remission-acc-body.ocs-reduction .bottom-p {
    font-family: "myriad-pro", sans-serif; font-weight: 700; font-style: normal; 
    font-size: 16px;
    line-height: 20px;
    color: #253139;
}

.remission-acc-body.ocs-reduction .acc-graphic img{max-width: 946px;}

#container-605a277fa5 #accordion-exa #acc-exa{border: unset;border-radius: unset;}
#container-605a277fa5 #accordion-exa .cmp-accordion__header{
    border: 1px solid #D7D7D7;
    padding: 16px 0;
    border-radius: 16px;
}

#container-605a277fa5 #accordion-exa .cmp-accordion__header:has(.cmp-accordion__button--expanded){
    border-radius: unset;
    border-top-left-radius: 16px;
    border-top-right-radius: 16px;
}
#container-605a277fa5 #accordion-exa .cmp-accordion__panel{
    border-radius: unset;
    border: 1px solid #D7D7D7;
    box-shadow: 0 4px 6px #0000000D;
}

#text-1eb8dd2868 > div > p:nth-child(3) {
    margin-bottom: 5px;
}


@media screen and (min-width: 992px) {

    #container-605a277fa5 #accordion-exa .cmp-accordion__title .acc-text1{padding-left: 16px;}
    #container-605a277fa5 #accordion-exa #acc-exa {margin: 0 auto 40px;}
    
    #container-605a277fa5 #accordion-exa .cmp-accordion__panel{padding: 18px 32px 39px;}

    .remission-data-nav ul li.active a::before {
        content: '';
        width: 40%;
        margin: 0 auto;
        height: 8px;
        border-radius: 10px 10px 0 0;
        background-color: #AE2573;
        position: absolute;
        left: 0;
        right: 0;
        bottom: 0;
    }

    .remission-data-nav ul li.active a::after {
        content: '';
        width: 0;
        height: 0;
        border-left: 12px solid transparent;
        border-right: 12px solid transparent;
        border-top: 14px solid #AE2573;
        position: absolute;
        left: 0;
        right: 0;
        bottom: 0;
        margin: 0 auto;
        margin-bottom: -10px;
    }

    .remission-data-nav ul li.nav-border::after {
        content: '';
        position: absolute;
        width: 2px;
        height: 32px;
        top: 20px;
        right: 0;
        background-color: #EDEDED;

    }
}


@media screen and (max-width: 1300px) {
    .discretion {
        padding: 10px 0 0 0; width: 42%;
    }

    .disease-egpa {
        padding: 30px 0 0 0;
    }
    .achived-percentage-list-one,
    .achived-percentage-list-three {
        width: 46%;
    }

    .achived-percentage-list-three {
        width: 36%;
    }
}

@media screen and (max-width: 991px) {

    .remission-acc-body h3 {
        font-size: 16px;
        line-height: 18px;
        margin-top: -5px;
    }

    .ocs-reduction-cards .data-card .card-body p {
        margin: 10px auto;
        width: 93%;
    }

    #ocs-remission-data > div > div > div.ocs-reduction-cards > div:nth-child(2) > div.card-body > p:nth-child(4) {
        font-size: 14px;
        line-height: 16px;
        margin-bottom: 0;
    }

    .reduce-ocs-patients-main .reduce-ocs-patients .cards-note {
        padding-right: 5px;
    }

    .ocs-reduction-cards .data-card .card-body {
        min-height: auto;
        padding: 11px 10px 20px;
    }

    .achived-remission-in h5 {
        margin: 10px 0 0;
    }

    .ocs-reduction-cards .data-card .card-body .card-graph-1 {
        max-width: 319px;
    }

    .achived-percentage-list.achived-percentage-list-two {
        width: 9%;
    }

    .remission-acc-body p {
        font-size: 17px;
        line-height: 19px;
    }

    #text-46e6e7cc03 > div > div > div > div:nth-child(1) > div.disease-egpa > div > div:nth-child(1) > h4 {
        width: 101%;
    }

    .remission-acc-body .acc-graphic .graphic-header p {
        font-size: 18px;
        line-height: 20px;
        max-width: 245px;
        margin: 0 auto;
    }

    .remission-acc-body .acc-graphic .graphic-note {
        margin: 12px 0 15px;
    }

    .remission-acc-body .acc-graphic {
        margin-top: 15px;
    }

    .remission-acc-body {
        gap: 10px;
    }

    .remission-acc-body .acc-graphic img.mobile-only {
        max-width: 312px;
        margin: 0 auto;
    }

    #remission-data #accordion-exa {
        margin-top: 12px;
    }

    .remission-mandara-study {
        padding: 33px 0 0;
    }

.remission-acc-body h2 {
    /*text-transform: uppercase;*/
    font-weight:700;
    font-size: 28px;
    line-height: 32px;
}
.disease-activity-col {
    gap: 16px;
}
    #remission-data .egpa-cta-footnote-block p:first-child br{
    display:none;
}
.ocs-reduction-cards .data-card .card-heading p{
   font-size: 18px;
    max-width: 71%;
    margin: 0 auto;
}
    #container-605a277fa5 #accordion-exa #acc-exa{margin:0 16px 40px;}
    #container-605a277fa5 #accordion-exa .cmp-accordion__panel{padding: 18px 16px 20px;border-radius: 0 0 13px 13px;}
    .disease-activity,.ocs-reduction-cards{flex-direction: column;}
    .reduce-ocs-patients-main {padding: 33px 0 0 0;}

    .banner-remission-data { padding:42px 0 45px 0;}
    .banner-remission-data  h1 span {
       display: block;
    }

    #remission-data div#reference-section p {
        padding-right: 5px;
    }

    #ocs-remission-data > div > div > p.graphic-note {
        margin-top: 30px;
    }

    .remission-mandara-study-head h2 {
        font-size: 28px;
        line-height: 30px;
        
    }
    .remission-mandara-study-head h2 br { display: block; }
    .patients-remission-main {
        display: block;
    }

    .patients-remission {
        max-width: 100%;
    }

    .patients-remission h3 {
        font-size: 19px;
        line-height: 22px;
    }

    .achived-remission-in > h5 {
        font-size: 18px;
        line-height: 22px;
        margin: 0 0 18px 0;
    }

    .achived-remission-in > p {
        font-size: 18px;
        line-height: 20px;
    }

    .achived-percentage>p {
        font-size: 41.85px;
        line-height: 44px;
        padding: 0 20px 0 0;
    }

    .achived-percentage>p>sub {
        font-size: 31.38px;
        line-height: 31.38px;
        bottom: 5px;
    }

    .achived-percentage>h3 {
        margin: 0 0 14px 0;
        font-size: 24px;
        line-height: 28px;
    }

    .achived-percentage>p {
        margin-left: 0;
    }

    #text-f3cda260a3 > div > div > div > div.patients-remission-main > div.patients-remission > div > div > div > div.achived-percentage-2 > p:nth-child(1) {
        padding-right: 10%;
        margin-top: 10px;
    }

    .achived-percentage-2 .percentage {
        font-size: 24px;
        line-height: 24px;
        bottom: 5px;
    }

    .achived-percentage-2>p {
        font-size: 32px;
        line-height: 36px;
    }

    #remission-data .flex-items {
        gap: 10px;
    }

    .achived-percentage-2 .normal-text,
    #remission-data .vs-text {
        font-size: 20px;
        line-height: 24px;
        margin-top: 0;
    }

    .achived-remission-in {
        padding: 22px 10px 5px 10px;
    }

    .patients-remission h6 {
        padding:0; 
        margin: 15px 0 0 0;
        font-size: 17px;
    }

    .patients-remission-disease {
        padding: 31px 0 0 0;
    }

    .patients-remission-disease p {
        font-size: 16px;
        line-height: 100%;
    }
.patients-remission-disease p > br {
    display: block;
}

    #remission-data .reduce-ocs-patients-head h2 {
        font-size: 28px;
        line-height: 30px;
        /* max-width: 290px; */
    }

    .investigator {
        display: block;
    }

    .discretion {
        width: 100%;
    }

    .reducing {
        width: 100%;
    }

    .reducing-in p br {
        display: none;
    }

    .discretion {
        padding: 22px 0 0 0;
    }

    .discretion h5 {
        text-align: center;
        font-size: 16px;
        line-height: 20px;
        padding: 0 0 1px 0;
    }

    .discretion p {
        max-width: 100%;
        text-align: center;
    }

    .reducing-in p {
        font-size: 18px;
        line-height: 22px;
    }

    .reducing-in {
        max-width: 290px;
        padding: 20px 15px 20px 15px;
    }

    .reduce-ocs-patients {
        padding: 39px 0 20px 0;
    }

    .disease-activity-head h2 {
        font-size: 28px;
        line-height: 30px;
        margin: 0;
        max-width: 290px;
    }

    #acc-exa-item-91602f213e-panel .remission-acc-body .acc-graphic img.mobile-only {
        max-width: 303px;
        margin: 0 auto 15px;
    }

    #text-1eb8dd2868 > div > p.bottom-p {
        margin-top: 10px;
    }

    #ocs-remission-data > div > div {
        padding-bottom: 10px;
    }

    .disease-egpa {
        padding: 0 0 0 0;
        /*padding: 24px 0 0 0;*/
        display: block;
    }

    .disease-egpa-content {
        padding: 0 0 32px 0;
        max-width: 100%;
    }

    .disease-egpa-activity {
        width: 100%;
    }

    .achived-remission-activity .achived-remission-in {
        padding: 25px 10px;
    }

    p.result-descriptive {
        padding: 22px 0 0 0;
        font-size: 18px;
        line-height: 20px;
    }

    .disease-activity {
        padding: 29px 0 0;
    }

    .egpa-cta-footnote-remission-data {
        padding: 24px 0 24px 0;
    }

    .remission-data-icon img {
        margin-right: 12px;
    }

    .daily-dose-content {
        padding: 32px 16px 32px 16px;
    }

    .enpoint-data {
        padding: 0px 0 24px 0;
    }

    .remission-data-nav {
        box-shadow: none;
        border: #D7D7D7 1px solid;
        padding: 0;
    }

    .enpoint-mepolizumab {
        display: block;
        max-width: 100%;
        padding: 0;
    }

    .enpoint-graph {
        padding: 0;
    }

    .eliminated-content {
        padding: 46px 0 0 0;
    }

    .eliminated-ocs h5 {
        margin: 3px 0 6px 0;
    }

    .remission-data-tab .remission-data-nav ul {
        display: block;
        max-width: 100%;
    }

    .remission-data-nav ul li {
        display: block;
        width: 100%;
    }

    .remission-data-nav ul li.nav-border::after {
        display: none;
    }

    .remission-data-nav ul li a {
        padding:18px 16px 16px 16px;
        text-align: left; font-size: 18px; line-height: 20px;
    }

    .remission-data-content-main {
        box-shadow: 0px 4px 6px 0px rgba(0, 0, 0, 0.08);
        border: #D7D7D7 1px solid;
    }

    .remission-data-nav ul li.nav-border {
        border-bottom: #D7D7D7 1px solid;
    }

    .remission-data-nav ul li a::before {
        content: url(/content/dam/intelligentcontent/brands/fasenra-hcp/en/images/fasenra-egpa/global/desktop/chevron-down.svg);
        position: absolute;
        right: 20px;
        background-repeat: no-repeat;
        top: 21px; 
    }

    .remission-data-nav ul li.active a::before {
        position: absolute;
        right: 20px;
        top: 16px; 

        background-repeat: no-repeat;
        transform: rotate(180deg);
        -webkit-transform: rotate(180deg);
        -moz-transform: rotate(180deg);
        -ms-transform: rotate(180deg);
        -o-transform: rotate(180deg);
    }
    .enpoint-mepolizumab1 .eliminated-ocs h4  {  max-width: 200px; margin: 0 auto; margin-top: 4px;}
    .enpoint-data h3 { max-width: 270px; margin: 0 auto; margin-bottom: 8px;}
    .descriptive p { padding: 0 10px;}
    .descriptive { padding: 30px 0 0 0;}
    .achived-percentage-main {  padding: 0;}
    .achived-percentage-list > p { font-size: 32px;
        line-height: 36px;}
        .achived-percentage-list > p > span {
    font-family: "Myriad-pro";
    font-size: 24px;
    line-height: 100%;
    }
    .achived-percentage-list > h4 { font-size: 20px; line-height: 24px;}
    .achived-percentage-list > h5 { font-size: 20px;  line-height: 24px;}
    .noninferiority-mandara { padding-top: 32px; } 
}

@media screen and (max-width: 767px) {}

@media screen and (max-width: 414px) { 
    .remission-mandara-study-head h2 { font-size: 27px;}
}

@media screen and (max-width: 379px) {
    .remission-acc-body .acc-graphic img.mobile-only,
    .ocs-reduction-cards .data-card .card-body .card-graph-2,
    .ocs-reduction-cards .data-card .card-body .card-graph-1 {
        max-width: 95% !important;
    }

    .achived-percentage-list-three > h6 {
        font-size: 20px;
        line-height: 24px;
    }

    .ocs-reduction-cards .data-card .card-body {
        min-height: max-content;
    }
}



/*Feedback 18-08-25 */
#remission-data .banner h1 {
    font-family: "myriad-pro-condensed", sans-serif; font-weight: 900; font-style: italic;
    font-weight: 900;
}

#remission-data .achived-percentage>h3, #remission-data .patients-remission h3, #remission-data .remission-acc-body h3 {
    font-family: "myriad-pro", sans-serif;
    font-weight: 700;
}

@media screen and (min-width: 991px) {

    #remission-data .cmp-accordion__button {
        padding: 4px 26px 7px !important;
    }
}